Taelo ea hoqetela e qala ha nanotechnology ea Desty Nova e tsosa Alita toropong e phaphametseng ea Tiphares. Liphiri tsa batho ba batsho tsa toropo li pepesitsoe ka sehloho, empa ho bonahala e le karoloana e nyane ea lefats'e e thata. Ha a kena sebakeng le likhamphani tsa khale le tse ncha ho ithuta haholoanyane ka lintho tse fetileng tseo a li lebetseng le ka ho lekana, ho ea batla motsoalle oa hae ea lahlehileng Lou Collins, Alita o tšoeroe ke ntoa e lipakeng tsa matla a maholo a sistimi ea letsatsi e neng e le kolone. Ha a le tseleng, o theha selekane le Alita Replicas tse tharo tse seng li qalile ho itšepa, superhacker e sa khahliseng, le Nova ka boeena ha a kenella Zenith of Things Tournament (ZOTT), tlholisano ea ntoa e tšoaroang lilemo tse ling le tse ling tse 10. Ho kenyelletsa tsela eo Lefatše le hlahileng ka eona nakong ea koluoa ea mariha e ileng ea felisa bongata ba sechaba ho pholletsa le pale ea nalane, nalane e ngoe e mabapi le boemo ba Battle Angel Alita e neng e sa senoloa khoeleng ea pejana e bonts'itsoe.
